Cyclic AMP binds to 

(A) Catalytic subunits of protein kinase 

(B) Regulatory subunits of protein kinase 

(C) Catalytic subunits of phosphorylase kinase 

(D) Regulatory subunits of phosphorylase kinase

Feedback inhibition of enzyme is influenced by 

(A) Enzyme 

(B) External factors 

(C) End product 

(D) Substrate

At low blood glucose concentration, brain but not liver will take up glucose. It is due to the 

(A) Low K_m of hexokinase 

(B) Low K_m of glucokinase 

(C) Specificity of glucokinase 

(D) Blood brain barrier 

Since pepsin is a gastric enzyme does it have an acid or basic optimum pH? What happens to pepsin when it passes into the duodenum?

Template/lock and key theory of enzyme action is supported by 

(A) Enzymes speed up reaction 

(B) Enzymes occur in living beings and speed up certain reactions 

(C) Enzymes determine the direction of reaction 

(D) Compounds similar to substrate inhibit enzyme activity

Fischer’s ‘lock and key’ model of the enzyme action implies that 

(A) The active site is complementary in shape to that of substance only after interaction. 

(B) The active site is complementary in shape to that of substance 

(C) Substrates change conformation prior to active site interaction 

(D) The active site is flexible and adjusts to substrate

Glycolysis is anaerobic in 

(A) Liver 

(B) Brain 

(C) Kidneys 

(D) Erythrocytes

‘Lock’ and ‘Key’ theory was proposed by

(A) Sorenson

(B) Fischer

(C) Mehler

(D) Sanger

Which of the following enzymes incorporates inorganic phosphate into the substrate? 

(A) Phosphoglycerate kinase 

(B) Glyceraldehyde-3-phosphate dehydrogenase 

(C) Pyruvate kinase 

(D) Enolase

In erythrocytes, 2, 3-biphosphoglycerate is derived from the intermediate: 

(A) Glyeraldehyde-3-phosphate 

(B) 1, 3-Biphosphoglycerate 

(C) 3-Phosphoglycerate 

(D) 2-Phosphoglycerate