Describe the hormonal feedback circuits in controlling renal finctions

1.	Describe the hormonal feedback circuits in controlling renal finctions
Answer» Regulation of kidney function involves feedback circuits.There are 3 main feedback systems that regulate the kidney functions.\xa01. Control by JGA:JGA operates multihormonal Renin-angiotensin-aldosterone system (RAAS). The JGA responds to a decrease in blood pressure or blood volume in the afferent arteriole of the glomerulus and releases an enzyme, renin, into the\xa0bloodstream. In the blood, renin initiates chemical reactions that convert a plasma protein called angiotensinogen to a peptide called angiotensin\xa0I. This is converted to angiotensin\xa0II\xa0in lungs by angiotensin converting enzyme. Angiotensin\xa0II\xa0acts on adrenal gland and results in the release of aldosterone from the adrenal gland. Aldosterone increases blood pressure and increases blood flow to the glomerulus. It acts on DCT and collecting duct and increases reabsorption of Na+.\xa02. Control by ADH:ADH is released from pituitary gland when osmolarity of blood is increased. It acts on DCT and collecting duct and helps in reabsorption of water.\xa03. Control by ANFAtrial Natriuretic Peptides (ANF) opposes the regulation by RAAS. ANF inhibits the release of renin from the JGA and\xa0thereby\xa0inhibits\xa0NaCl\xa0reabsorption by collecting duct and reduces aldosterone release from the\xa0adrenal gland.\xa0

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