InterviewSolution
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InterviewSolution
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Glycolysis isA. oxidation of glucose to pyruvateB. conversion of glucose to haemC. oxidation of glucose to glutamateD. conversion of pyruvate to citrate |
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Answer» Correct Answer - A Most tissues have at least a minimal requirement for glucose. In some cases, e.g., brain, the requirement is substantial, while in other, e.g., erythrocytes, it is nearly total. Glycolysis is the major pathway for the utilization of glucose and is formed in the cytosol of all cells. It is a unique pathway, since it can utilize oxygen if available via the respiratory chain in mitochondria (aerobic), or it can function in the absense of oxygen (anaerobic). Glycolysis, the first stage in oxidation of glucose, involves the degradation of glucose into two molecules of pyruvate (anion of pyruvic acid, `CH_(3) COCO_(2)H)` with the generation of two molecules of `ATP` in an anaerobic process. To oxidize glucose beyond the pyruvate end stage og glycolysis requires not only molecular `O_(2)` but also mitochondrial enzyme systems such as the pyruvate dehydrogenase complex, the citric and cycle, and the respiratory chain. |
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