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In which case a cofactor becomes a prosthetic group.

Answer» A cofactor that firmly attaches to the apoenzyme is called prosthetic group.Prosthetic groups are organic compounds and are distinguished from other cofactors in that they are tightly bound to the apoenzyme. For example, in peroxidase and catalase, which catalyze the breakdown of hydrogen peroxide to water and oxygen, haem is the prosthetic group and it is a part of the active site of the enzyme. Cofactor may be organic or inorganic (metal ions).


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