InterviewSolution
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J-159. Describe the Fluid Mosaic Model of cell membrane with diagram 5 |
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Answer» Thefluid mosaic model describesthe structure of theplasma membraneas amosaicof components —including phospholipids, cholesterol, proteins, and carbohydrates—that gives themembraneafluidcharacter.Plasma membranesrange from 5 to 10 nm in thickness. ... For example, myelin contains 18% protein and 76% lipid. The fluid mosaic model of cell membranes- Substances that make up the cell membrane are not locked in place - arranged in a 'mosaic' but are free to move around within the mosa Thefluid mosaic modelexplains various observations regarding the structure of functionalcell membranes. According to thisbiological model, there is alipid bilayer(two molecules thick layer) in whichproteinmoleculesare embedded. The lipid bilayer givesfluidityandelasticityto themembrane. Small amounts ofcarbohydratesare also found in the cell membrane. The biological model, which was devised bySJ SingerandG. L. Nicolsonin 1972, describes the cell membrane as atwo-dimensional liquidthat restricts thelateral diffusionof membrane components. Such domains are defined by the existence of regions within the membrane with special lipid and protein cocoon that promote the formation oflipid raftsor protein andglycoproteincomplexes. Another way to define membrane domains is the association of the lipid membrane with thecytoskeletonfilaments and theextracellular matrixthrough membrane proteins. The current model describes important features relevant to many cellular processes, including:cell-cell signaling,apoptosis,cell division, membrane budding, and cell fusion. The fluid mosaic model is the most acceptable model of the plasma membrane. Its main function is to give shape to the cell. Thefluid mosaic modelexplains various observations regarding the structure of functionalcell membranes. According to thisbiological model, there is alipid bilayer(two molecules thick layer consisting primarily of amphipathic phospholipids) in whichproteinmoleculesare embedded. The lipid bilayer givesfluidityandelasticityto themembrane. Small amounts ofcarbohydratesare also found in the cell membrane. The biological model, which was devised bySJ SingerandG. L. Nicolsonin 1972, describes the cell membrane as atwo-dimensional liquidthat restricts thelateral diffusionof membrane components. Such domains are defined by the existence of regions within the membrane with special lipid and protein cocoon that promote the formation oflipid raftsor protein andglycoproteincomplexes. Another way to define membrane domains is the association of the lipid membrane with thecytoskeletonfilaments and theextracellular matrixthrough membrane proteins.[1]The current model describes important features relevant to many cellular processes, including:cell-cell signaling,apoptosis,cell division, membrane budding, and cell fusion. The fluid mosaic model is the most acceptable model of the plasma membrane. Its main function is to separate the contents of the cell from the outside. |
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