Justify the statements. If the answer is false, change the underlined

1.	Justify the statements. If the answer is false, change the underlined word(s) to make the statement true. (i) The DNA molecule is double stranded and the RNA molecule is single stranded.(ii) The process of translation occurs at the ribosome.(iii) The job of m-RNA is to pick up amino acids and transport them to the ribosomes.(iv) Transcription must occur before translation may occur.
Answer» (i) 1. DNA as the genetic material has to be chemically and structurally stable. 2. It should be able to generate its replica. 3. Sugar-phosphate backbone and complementary base pairing between the two strands, give stability to DNA. 4. Both the strands of DNA act as template for synthesis of their complementary strands. This allows accurate replication of DNA. 5. Single stranded RNA can be folded to form complex structures and perform specific functions such as synthesis of proteins (ii) 1. Translation is the process in which sequence of codons of m-RNA is decoded and accordingly amino acids are added in specific sequence to form a polypeptide on ribosomes. 2. Ribosome has one binding site for mRNA. It orients m-RNA molecule in such a way that all the codons are properly read. 3. Ribosome has three binding sites for tRNA : P-site (peptidyl t-RNA-site), Asite (aminoacyl t-RNA-site) and E-site (exit site). 4. t-RNAs place the required amino acids in correct sequence and translate the coded message of RNA. 5. In eukaryotes, a groove which is present between two subunits of ribosomes, protects the polypeptide chain from the action of cellular enzymes and also protects m-RNA from the action of nucleases. 6. Thus ribosome plays an important role in translation. (iii) The job of t-RNA is to pick up amino acids and transport them to ribosomes. t-RNA is an adapter molecule. It reads the codons of mRNA and also simultaneously transfer specific amino acid to m-RNA Ribosome complex. It binds with amino acid at its 3′ end. (iv) In prokaryotes, translation can start before transcription is complete, as both these processes occur in the same compartment, i.e. cytoplasm. But in eukaryotes, transcription and processing of hnRNA occurs in nucleus. hnRNA then comes out of the nucleus through nuclear pores and then it is translated at ribosomes in the cytoplasm.

Justify the statements. If the answer is false, change the underlined word(s) to make the statement true. (i) The DNA molecule is double stranded and the RNA molecule is single stranded.(ii) The process of translation occurs at the ribosome.(iii) The job of m-RNA is to pick up amino acids and transport them to the ribosomes.(iv) Transcription must occur before translation may occur.

Answer»

(i) 1. DNA as the genetic material has to be chemically and structurally stable.

2. It should be able to generate its replica.

3. Sugar-phosphate backbone and complementary base pairing between the two strands, give stability to DNA.

4. Both the strands of DNA act as template for synthesis of their complementary strands. This allows accurate replication of DNA.

5. Single stranded RNA can be folded to form complex structures and perform specific functions such as synthesis of proteins

(ii) 1. Translation is the process in which sequence of codons of m-RNA is decoded and accordingly amino acids are added in specific sequence to form a polypeptide on ribosomes.

2. Ribosome has one binding site for mRNA. It orients m-RNA molecule in such a way that all the codons are properly read.

3. Ribosome has three binding sites for tRNA : P-site (peptidyl t-RNA-site), Asite (aminoacyl t-RNA-site) and E-site (exit site).

4. t-RNAs place the required amino acids in correct sequence and translate the coded message of RNA.

5. In eukaryotes, a groove which is present between two subunits of ribosomes, protects the polypeptide chain from the action of cellular enzymes and also protects m-RNA from the action of nucleases.

6. Thus ribosome plays an important role in translation.

(iii) The job of t-RNA is to pick up amino acids and transport them to ribosomes. t-RNA is an adapter molecule. It reads the codons of mRNA and also simultaneously transfer specific amino acid to m-RNA Ribosome complex. It binds with amino acid at its 3′ end.

(iv) In prokaryotes, translation can start before transcription is complete, as both these processes occur in the same compartment, i.e. cytoplasm. But in eukaryotes, transcription and processing of hnRNA occurs in nucleus. hnRNA then comes out of the nucleus through nuclear pores and then it is translated at ribosomes in the cytoplasm.

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