What is TCA cycle.write its role is in respiration.?

1.	What is TCA cycle.write its role is in respiration.?
Answer» The TCA cycle\xa0is\xa0a\xa0central pathway into which many metabolites feed. It consists of\xa0a\xa0number of reactions which generate NADH and FADH₂ which can in turn be used by\xa0the oxidative phosphorylation\xa0pathway to generate ATP.\xa0The TCA cycle\xa0occurs in\xa0the\xa0matrix of\xa0the\xa0mitochondria.\xa0The\xa0citric acid cycle\xa0is a series of reactions that\xa0produces\xa0two carbon dioxide molecules, one GTP/ATP, and reduced forms of NADH and FADH2.\xa0The regulation of the rate of oxidative phosphorylation by the ADP level is called\xa0respiratory control\xa0or acceptor\xa0control. The level of ADP likewise affects the rate of the\xa0citric acid cycle\xa0because of its need for NAD+\xa0and FAD. The physiological significance of this regulatory mechanism is evident.\xa0The major significance of the citric acid cycle is to act as the final common pathway for the oxidation of carbohydrates, lipids and proteins, since\xa0glucose, fatty acids and many amino acids are all metabolised to acetyl CoA.

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