What is the reason for inflammation by the release of histamine by mas

1.	What is the reason for inflammation by the release of histamine by mast cells
Answer» Histamine\xa0is not only\xa0released\xa0when the body encounters a toxic substance, it is also\xa0released\xa0when\xa0mast cells\xa0detect injury. It\xa0causes\xa0nearby blood vessels to dilate allowing more blood to reach the site of the injury or\xa0infection.\xa0The Fc region of immunoglobulin E (IgE) becomes bound to\xa0mast cells\xa0and basophils and when IgE\'s paratopes bind to an antigen, it\xa0causes\xa0the\xa0cells to release histamine\xa0and other inflammatory mediators. These similarities have led many to speculate that\xa0mast cells\xa0are basophils that have "homed in" on tissues.\xa0Histamine\xa0is involved in the\xa0inflammatory response\xa0and has a central\xa0role\xa0as a mediator of itching. ...\xa0Histamine\xa0increases the permeability of the capillaries to white blood cells and some proteins, to allow them to engage pathogens in the infected tissues.

What is the reason for inflammation by the release of histamine by mast cells