A 35-year-old Woman Presents With Cervical Lymphadenopathy And Sympto

1.	A 35-year-old Woman Presents With Cervical Lymphadenopathy And Symptoms Of Fever, Night Sweats, And Weight Loss. An Excisional Biopsy Of A Supraclavicular Lymph Node Reveals Nodular Sclerosing Hodgkin's Lymphoma. Staging Pet-ct Shows Bulky Mediastinal Lymphadenopathy (mediastinal/thoracic Ratio > 1/3), And She Has A Baseline Erythrocyte Sedimentation Rate (esr) Of 50 Mm/h. What Favorable Prognostic Feature Does This Patient Have For Early-stage Hodgkin's Lymphoma?
Answer» TUR remains the SURGICAL mainstay for the DIAGNOSIS and treatment of stages Ta and T1 bladder cancer. After this procedure, the 10-year disease-specific SURVIVAL for Ta tumors is 85% and for T1 tumors it is 70%. The initial TUR provides pathologic material to determine the histologic type, grade, and depth of invasion. The findings help to direct additional therapy, dictate the follow-up schedule, and indicate prognosis. In a literature review of more than 600 cases of T1 bladder tumors treated only by TUR, 75% to 90% recurred by 5- and 10-year follow-up. A third of the cancers progressed to muscle invasion within 5 YEARS, 39% had progressed by 10 years, and 53% by 15 years. TUR remains the surgical mainstay for the diagnosis and treatment of stages Ta and T1 bladder cancer. After this procedure, the 10-year disease-specific survival for Ta tumors is 85% and for T1 tumors it is 70%. The initial TUR provides pathologic material to determine the histologic type, grade, and depth of invasion. The findings help to direct additional therapy, dictate the follow-up schedule, and indicate prognosis. In a literature review of more than 600 cases of T1 bladder tumors treated only by TUR, 75% to 90% recurred by 5- and 10-year follow-up. A third of the cancers progressed to muscle invasion within 5 years, 39% had progressed by 10 years, and 53% by 15 years.

A 35-year-old Woman Presents With Cervical Lymphadenopathy And Symptoms Of Fever, Night Sweats, And Weight Loss. An Excisional Biopsy Of A Supraclavicular Lymph Node Reveals Nodular Sclerosing Hodgkin's Lymphoma. Staging Pet-ct Shows Bulky Mediastinal Lymphadenopathy (mediastinal/thoracic Ratio > 1/3), And She Has A Baseline Erythrocyte Sedimentation Rate (esr) Of 50 Mm/h. What Favorable Prognostic Feature Does This Patient Have For Early-stage Hodgkin's Lymphoma?

Answer»

TUR remains the SURGICAL mainstay for the DIAGNOSIS and treatment of stages Ta and T1 bladder cancer. After this procedure, the 10-year disease-specific SURVIVAL for Ta tumors is 85% and for T1 tumors it is 70%. The initial TUR provides pathologic material to determine the histologic type, grade, and depth of invasion. The findings help to direct additional therapy, dictate the follow-up schedule, and indicate prognosis. In a literature review of more than 600 cases of T1 bladder tumors treated only by TUR, 75% to 90% recurred by 5- and 10-year follow-up. A third of the cancers progressed to muscle invasion within 5 YEARS, 39% had progressed by 10 years, and 53% by 15 years.

TUR remains the surgical mainstay for the diagnosis and treatment of stages Ta and T1 bladder cancer. After this procedure, the 10-year disease-specific survival for Ta tumors is 85% and for T1 tumors it is 70%. The initial TUR provides pathologic material to determine the histologic type, grade, and depth of invasion. The findings help to direct additional therapy, dictate the follow-up schedule, and indicate prognosis. In a literature review of more than 600 cases of T1 bladder tumors treated only by TUR, 75% to 90% recurred by 5- and 10-year follow-up. A third of the cancers progressed to muscle invasion within 5 years, 39% had progressed by 10 years, and 53% by 15 years.

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