InterviewSolution
| 1. |
A 57-year-old, Obese White Man Has Symptoms Of Chronic Gastroesophageal Reflux Disease (gerd). Endoscopic Evaluation Reveals Evidence Of Barrett's Esophagus With High-grade Dysplasia. What Is The Recommended Management For This Disease? |
|
Answer» The American COLLEGE of Gastroenterology guidelines state that "patients with chronic GERD SYMPTOMS are those who are most likely to have Barrett's esophagus and should undergo upper endoscopy." However, the grade of dysplasia determines the interval for surveillance endoscopy. In patients without dysplasia on 2 consecutive endoscopies with biopsies, a 3- to 5-year interval has been proposed. For patients with low-grade dysplasia, annual surveillance is recommended. For patients with high-grade dysplasia, a MUCOSAL resection should be attempted and the grade of dysplasia identified carefully by an expert gastrointestinal pathologist. ENDOSCOPIC ablation therapies can be considered as a viable alternative to surgery in this patient population. The American College of Gastroenterology guidelines state that "patients with chronic GERD symptoms are those who are most likely to have Barrett's esophagus and should undergo upper endoscopy." However, the grade of dysplasia determines the interval for surveillance endoscopy. In patients without dysplasia on 2 consecutive endoscopies with biopsies, a 3- to 5-year interval has been proposed. For patients with low-grade dysplasia, annual surveillance is recommended. For patients with high-grade dysplasia, a mucosal resection should be attempted and the grade of dysplasia identified carefully by an expert gastrointestinal pathologist. Endoscopic ablation therapies can be considered as a viable alternative to surgery in this patient population. |
|