1.

A 63-year-old Man With A Remote History Of Tobacco Use Presents With Hematuria. He Undergoes A Transurethral Resection (tur), Which Reveals T1 Superficial Bladder Cancer. What Is His Risk For Bladder Cancer Recurrence In The Next 5 Years Without Further Therapy?

Answer»

TUR remains the surgical mainstay for the DIAGNOSIS and treatment of stages Ta and T1 bladder cancer. After this procedure, the 10-year disease-specific survival for Ta tumors is 85% and for T1 tumors it is 70%. The initial TUR provides pathologic material to determine the histologic type, grade, and DEPTH of invasion. The findings help to direct additional therapy, dictate the follow-up schedule, and indicate prognosis. In a literature review of more than 600 cases of T1 bladder tumors treated only by TUR, 75% to 90% recurred by 5- and 10-year follow-up. A third of the cancers progressed to muscle invasion within 5 years, 39% had progressed by 10 years, and 53% by 15 years.

TUR remains the surgical mainstay for the diagnosis and treatment of stages Ta and T1 bladder cancer. After this procedure, the 10-year disease-specific survival for Ta tumors is 85% and for T1 tumors it is 70%. The initial TUR provides pathologic material to determine the histologic type, grade, and depth of invasion. The findings help to direct additional therapy, dictate the follow-up schedule, and indicate prognosis. In a literature review of more than 600 cases of T1 bladder tumors treated only by TUR, 75% to 90% recurred by 5- and 10-year follow-up. A third of the cancers progressed to muscle invasion within 5 years, 39% had progressed by 10 years, and 53% by 15 years.



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