1.

A human being suffering from Down’s Syndrome shows trisomy of 21st chromosome. Mention the cause of this chromosomal abnormality

Answer»

Due to non-disjunction, 21st pair of chromosomes fail to separate during oogenesis. Therefore, the egg possesses 24 chromosomes instead of 23. When the egg fuses with a sperm, the zygote will have three copies of chromosome 21 causing trisomy.



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