A person is born with a hereditary disease with a weakened immune syst

1.	A person is born with a hereditary disease with a weakened immune system due to deficiency of an enzyme. Suggest a technique for complete cure for this disease. Identify the deficient enzyme and explain the technique used for cure.
Answer» Gene Therapy ADA (Adenosine deaminase) deficiency Lymphocytes from the blood of the patient are grown in a culture, a functional ADA cDNA is introduced into these lymphocytes, which are subsequently returned to the patient. The permanent cure is done by introducing ADA cDNA into cells at early embryonic stages.

A person is born with a hereditary disease with a weakened immune system due to deficiency of an enzyme. Suggest a technique for complete cure for this disease. Identify the deficient enzyme and explain the technique used for cure.

Answer»

Gene Therapy

ADA (Adenosine deaminase) deficiency Lymphocytes from the blood of the patient are grown in a culture, a functional ADA cDNA is introduced into these lymphocytes, which are subsequently returned to the patient. The permanent cure is done by introducing ADA cDNA into cells at early embryonic stages.

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A person is born with a hereditary disease with a weakened immune system due to deficiency of an enzyme. Suggest a technique for complete cure for this disease. Identify the deficient enzyme and explain the technique used for cure.

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