InterviewSolution
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InterviewSolution
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A primary amine, RNH_(2) can be reacted with CH_(3)-X to get secondary amine, R-NHCH_(3) but the only disadvantage is that 3^(@) amine and quaternary ammonium salts are also obtained as side products. Can you suggest a method where RNH_(2) forms only 2^(@) amines? |
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Answer» Solution :`1^(@)` Amines REACT with `CHCl_(3)` in presence of alcoholic KOH to form isocyanides which UPON catalytic reduction give `2^(@)` amines. `underset(1^(@)" Amine")(RNH_(2)) underset(("Carbylamine reaction"))OVERSET(KOH//CHCl_(3))to R-overset(to)(=)C underset(("Catalytic reduction"))overset(H_(2)//Pt)to underset(2^(@)" amine")(R-NH-CH_(3))` |
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