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Alteration of which genes leads to cancerA. Cell proliferation gene (proto-oncogenes)B. Tumor suppressor geneC. Tumor virus geneD. All of these

Answer» Correct Answer - A
(a) In human being cancer is caused by extra-activation of certain genes called proto-oncogenes into cellular oncogenes. Proto- oncogenes typically encode proteins receptors, signal transduction proteins, and transcription factors. Multation in these genes tend to relax control mechanisms and accelerate cell division, leading to cell proliferation that is characteristic of cancer. Tumor suppressor gene normally keeps mitosis in check & prevent cancer from occuring.


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