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| 1. |
Answer any FOUR of the following questions. b. How do you prepare methoxy ethane by Williamson's ether synthesis? |
Answer» SOLUTION :(a) Step 1 : FORMATION of proptonated alcohol. Step 2 : Formation of carboncation : `H-UNDERSET(H)underset(|)overset(H)overset(|)(C )-underset(H)underset(|)overset(H)overset(|)(C )-overset(H)overset(|)(underset(ddot)O)-Hoverset("Slow")( ![]() (b) When sodium sodium ethoxide is heated with methyl iodide (in alcoholic medium), methoxyethane is formed `underset("Sodium ethoxide")(CH_3CH_2)-ONa) + underset("Methoxy iodine")(I-CH_3) underset(Delta)overset("Alcohol")(rarr)underset("Methoxy methane")(CH_3CH_2-O-CH_3+NaI)` DETAILED ANSWER: (b) In a Williamson synthesis, an ether is formed by reacting an alcohol and an alkyl halide in the presence of a base. When `CH_3-I` is mixed with the base, like `NaOH`, the alcohol is deprotonated, leaving a negatively charged oxygen. This acts as a nucleophile and attacks the carbon bonded to the halogen(iodide). The halogen, a good leaving group, is released, leaving behind methoxy ethane. |
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