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Assertion: Reductive amination involves the transfer of amino group from one amino acid to the keto group of a keto acid. Reason: In reductive amination, transfer of `NH_(2)` from glutamic acid takes place.A. If both assertio and reason are true and reason is the correct explanation of assertionB. if both assertion and reason are true but reason is not the correct explanation of assertionC. if assertion is true but reason is falseD. if both assertion and reason are false |
Answer» Correct Answer - D In reductive amination in the presence of enzyme glutamate dehydrogenase and a reduced coenzyme (NADH or NADPH), ammonia can directely combine with `alpha`-ketoglutaric acid to from a an amino acid. On the other hand, transamination is transfer of amino group `(-NH_(2))` of one amino acid with the keto group (gt C=O) of keto acid. in transaminase, transfer of `NH_(2)` from glutamic acid takes place. The enzyme required is transaminase or aminostransferase. |
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