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d) The drug undergoes rapid distribution initially.19. The plasma elimination half-life of a drug:a) Is inversely related to its clearance.b) Is shorter after intravenous compared to oral administration.c) Is not affected by changes in its apparent volume of distribution.d) Largely determines its duration of action.20. With regards to binding of drugs to plasma proteins:a) Binding tends to limit the elimination of drugs which undergo renal tubular sb) Binding ne the greater the degree of binding of a drug, the longer will be its half-life.c) Hypoalbuminemia can cause an increase in total plasma concentration of se d) A drug with a low binding capacity is more likely to cause adverse effects displaced from binding.21. Which of the following cytochrome P450 isoenzymes is involved in the me |
| Answer» Is shorter after intravenous compared to oral administration | |