1.

Describe glomerular filtration in human nephrons.

Answer»

The glomerular capillaries are narrower than the afferent renal arterioles, therefore the blood pressure in the glomerular capillaries becomes very high and there is continuous process of ultrafiltration through the semi-permeable glomerular capillaries. 

Filtration of blood occurs through three layers: 

(i) The endothelium of glomerular blood vessels. 

(ii) The epithelium of Bowman's capsule and 

(iii) The basement membrane between the two layers. The epithelial cells of Bowman's capsule called podocytes are arranged intricately so as to leave minute spaces called filtration slits. The glomerular filtrate and blood plasma are similar except that glomerular filtrate does not have proteins and fats.



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