Describe the carbobenzoxy method of synthesis of peptides

1.	Describe the carbobenzoxy method of synthesis of peptides
Answer» tion:The C-terminal residue is determined by the use of EITHER a chemical REAGENT or the enzyme carboxypeptidase. The chemical reagent hydrazine forms aminoacyl hydrazides with every residue except the C terminus (Figure 3-10). The C terminus is thus readily identified by CHROMATOGRAPHIC PROCEDURES. The disadvantage of hydrazinolysis is that the entire sample is used to DETERMINE just one residue.

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