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Desirable properties of a radionuclide for imaging include: a. High levels of cross-reactivity with blood proteins b. A half-life measured in hours, not minutes or days c. It decays to a stable daughter d. Low activity per unit volume e. Emission of beta particles |
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Answer» a. False. This would result in high blood pool activity, which may reduce uptake in the target organ. b. True. The half-life should ideally be a few hours, roughly equal to the time from injection to scanning. c. True. Decay should be to a stable daughter in order to minimize the dose to the patient. d. False. A radionuclide should have a high specific activity, i.e. high activity per unit volume. e. False. Beta particles act as secondary electrons and deposit an unnecessary dose in patients. |
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