| Excretion | Secretion |
| 1. It is the removal of materials from a living being. | 1. It is movement of material from one point to other point. |
| 2. Excretion is passive in nature. | 2. Secretion is active in nature. |
| 3. Humans excrete materials such as tears, urine, carbon dioxide and sweat. | 3. Humans secretions includes enzymes, hormones and saliva. |
| 4. Excretion is mostly body waste. | 4. Secretion is important materials that can be metabolized and used by our bodies. |
| 5. Plants excrete through roots into its surroundings and falling off leaves and bark. | 5. Secretions occur in the plant body in the form of latex, resins, gums etc. |