InterviewSolution
Saved Bookmarks
| 1. |
Difference between the key and look model and induced fit modal |
| Answer» In this analogy, the\xa0lock\xa0is the enzyme and the\xa0key\xa0is the substrate. Only the correctly sized\xa0key\xa0(substrate) fits into the\xa0key\xa0hole (active site) of the\xa0lock\xa0(enzyme). The\xa0induced-fit\xa0theory assumes that the substrate plays a role in determining the final shape of the enzyme and that the enzyme is partially flexible.\xa0The\xa0induced fit model\xa0describes the formation of the E-S complex as a result of the interaction between the substrate and a flexible active site. The substrate produces changes in the conformation on the enzyme aligning properly the groups in the enzyme. It allows\xa0better\xa0binding and catalytic effects. | |