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Discuss briefly how a probe is used in molecular diagnostics.

Answer» Early detection of a disease is not possible by conventional diagnostic methods. So. Some techniques have been implanted for early diagnosis like PCR, recombinant DNA technology and ELISA.
in recombinant DNA technology, a probe is used. It is allowed to hybridise to its complementary DNA in the clone of cells. the cells are then detected by autoradiography
The cell with mutated gane will not be observed on the photographic film becuase the probe will not h ave complementarity with the mutated gene.


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