Explain enzyme-replacement therapy to treat adenosine deaminase defici

1.	Explain enzyme-replacement therapy to treat adenosine deaminase deficiency. Mention two disadvantages of this procedure.
Answer» Functional adenosine is given to the patient by injection. Disadvantages : Therapy is not completely curative periodic infusion of enzyme required. Detailed Answer : Adenosine deaminase deficiency is a genetic disorder. The disorder is caused due to the deletion of the gene for adenosine deaminase, the enzyme crucial for the immune system to function. Adenosine deaminase deficiency in patients can be treated by enzyme replacement therapy. In this treatment, patients are regularly injected with the functional ADA enzyme. Disadvantages of this Process : (a) It does not completely eradicate the disease. (b) The requirement of repeated doses of the enzymes makes it expensive.

Explain enzyme-replacement therapy to treat adenosine deaminase deficiency. Mention two disadvantages of this procedure.

Answer»

Functional adenosine is given to the patient by injection.

Disadvantages :

Therapy is not completely curative periodic infusion of enzyme required.

Detailed Answer :

Adenosine deaminase deficiency is a genetic disorder. The disorder is caused due to the deletion of the gene for adenosine deaminase, the enzyme crucial for the immune system to function.

Adenosine deaminase deficiency in patients can be treated by enzyme replacement therapy. In this treatment, patients are regularly injected with the functional ADA enzyme.

Disadvantages of this Process :

(a) It does not completely eradicate the disease.

(b) The requirement of repeated doses of the enzymes makes it expensive.

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