Explain Rh factor incompatibility during pregnancy.

1.	Explain Rh factor incompatibility during pregnancy.
Answer» The human beings who have antigen on RBCs are Rh⁺ while others who do not have are Rh. It is through Rh⁺ is dominated over Rh- which is recessive. In a marriage between Rh^– woman and Rh+ man, when a woman become pregnant, she becomes sensitive while carrying a first Rh⁺ child within her womb. It is because some of RBCs from the developing embryo get into the blood stream of mother during development causing her to produce anti-Rh-antibodies. The first child of such parents is normal and is delivered safely. However, if such a mother get pregnant again the resulting Rh⁺ foetuses will be exposed to anti-Rh-bodies produced by the mother. As a result serious damage to RBCs of the developing embryo will occur causing erythroblastosis foetilis. The disease leads to the death of the developing embryo before birth or after parturition.

Answer»

The human beings who have antigen on RBCs are Rh⁺ while others who do not have are Rh. It is through Rh⁺ is dominated over Rh- which is recessive.

In a marriage between Rh^– woman and Rh+ man, when a woman become pregnant, she becomes sensitive while carrying a first Rh⁺ child within her womb. It is because some of RBCs from the developing embryo get into the blood stream of mother during development causing her to produce anti-Rh-antibodies. The first child of such parents is normal and is delivered safely. However, if such a mother get pregnant again the resulting Rh⁺ foetuses will be exposed to anti-Rh-bodies produced by the mother.

As a result serious damage to RBCs of the developing embryo will occur causing erythroblastosis foetilis. The disease leads to the death of the developing embryo before birth or after parturition.

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