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Explain the mechanism of nucleophilic substitution reaction sn1,sn2 and snAr |
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Answer» tion:nucleophilic aromatic substitution is a substitution reaction in organic chemistry in which the NUCLEOPHILE displaces a good leaving group, such as a halide, on an aromatic ring. There are 6 nucleophilic substitution mechanisms encountered with aromatic systems:the SNAr (addition-elimination) mechanismSNAr mechanismthe aromatic SN1 mechanism encountered with diazonium saltsAromatic SN1mechanismthe benzyne mechanism (E1cb-AdN)Substitution via benzynethe FREE radical SRN1 mechanismthe ANRORC mechanismVicarious nucleophilic substitution.The most important of these is the SNAr mechanism, where electron withdrawing groups activate the ring TOWARDS nucleophilic attack, for EXAMPLE if there are nitro functional groups positioned ortho or para to the halide leaving group |
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