Explain Why Acyclovir Is Selectively Toxic To Cells Infected By Alpha

1.	Explain Why Acyclovir Is Selectively Toxic To Cells Infected By Alpha-herpesviruses?
Answer» These viruses ENCODE their own thymidine kinase ENZYMES, which are needed for activation (phosphorylation) of the DRUG. Cellular thymidine kinase does not ACTIVATE the drug. These viruses encode their own thymidine kinase enzymes, which are needed for activation (phosphorylation) of the drug. Cellular thymidine kinase does not activate the drug.

Explain Why Acyclovir Is Selectively Toxic To Cells Infected By Alpha-herpesviruses?

Answer»

These viruses ENCODE their own thymidine kinase ENZYMES, which are needed for activation (phosphorylation) of the DRUG. Cellular thymidine kinase does not ACTIVATE the drug.

These viruses encode their own thymidine kinase enzymes, which are needed for activation (phosphorylation) of the drug. Cellular thymidine kinase does not activate the drug.

Discussion

No Comment Found

Related InterviewSolutions

List At Least Three Viruses Capable Of Causing (meningoencephalitis?
Mention At Least 4 Opportunistic Infections Characteristic For Aids?
Describe The 2 Different Epidemiological Cycles Of Yellow Fever?
What Does The Term Arbovirus Mean? Write An Example For An Arbovirus!
What Does The Term Robovirus Mean? Write An Example For A Robovirus?
What Is The Principle Of The „highly Active Antiretroviral Therapy” (haart) Currently Used In The Treatment Of Aids?
Mention 3 Nucleoside (or Nucleotide) Type Reverse Transcriptase Inhibitors Used In The Therapy Of Aids?
Mention 3 Human Prion Diseases?
What Are The Possible Consequences Of Fetal Infections Caused By Rubella Virus? Specify At Least 3 Of Them?
Mention At Least Two Viruses Frequently Causing Pneumonia?

Explain Why Acyclovir Is Selectively Toxic To Cells Infected By Alpha-herpesviruses?

Discussion

No Comment Found

Related InterviewSolutions

Reply to Comment