InterviewSolution
Saved Bookmarks
InterviewSolution
| 1. |
Glucose reabsorption in the renal tubules |
| Answer» <html><body><p><strong>Explanation:</strong></p><p>Renal glucose reabsorption is the part of kidney physiology that deals with the retrieval of filtered glucose, preventing it from disappearing from the body through the urine. If glucose is not reabsorbed by the kidney, it appears in the urine, in a condition known as glycosuria. This is associated with diabetes mellitus.</p><p>Firstly, the glucose in the proximal tubule is co-transported with sodium ions into the proximal convoluted tubule walls via the SGLT2 cotransporter. Some (<a href="https://interviewquestions.tuteehub.com/tag/typically-715673" style="font-weight:bold;" target="_blank" title="Click to know more about TYPICALLY">TYPICALLY</a> smaller) amino acids are also transported in this way. Once in the tubule <a href="https://interviewquestions.tuteehub.com/tag/wall-1448655" style="font-weight:bold;" target="_blank" title="Click to know more about WALL">WALL</a>, the glucose and amino acids diffuse <a href="https://interviewquestions.tuteehub.com/tag/directly-955045" style="font-weight:bold;" target="_blank" title="Click to know more about DIRECTLY">DIRECTLY</a> into the blood capillaries along a concentration gradient. This blood is flowing, so the gradient is maintained. Lastly, sodium/potassium ion active transport pumps <a href="https://interviewquestions.tuteehub.com/tag/remove-1184766" style="font-weight:bold;" target="_blank" title="Click to know more about REMOVE">REMOVE</a> sodium from the tubule wall and the sodium is <a href="https://interviewquestions.tuteehub.com/tag/put-11868" style="font-weight:bold;" target="_blank" title="Click to know more about PUT">PUT</a> back into the blood. This maintains a sodium concentration gradient in the proximal tubule lining, so the first step continues to happen.</p></body></html> | |