1.

Glycin has the structural formula `NH_(2)-CH_(2)-COOH`. Glycine has two dissociation constant for which `K_(a)" and " K_(b)` are `1.6xx10^(-10)" and "K_(b) is 2.5xx10^(12)`. Calculate the isoelectric point of glycine [Hint : If your answer is 5.12 then fill 0512 in OMR sheet. If your answer is 8.02 then fill 0802 in OMR sheet]

Answer» Correct Answer - 609
`pI=overset(pK_(a1)+pK_(a2))underset(2)_" "pK_(a)=-logK_(a)`
`=(9.7958+2.39)/2=6.09`
`pK_(a1)=-logK_(a)" "pK_(b1)=-logK_(b)`
`pK_(a1)=-log1.6xx10^(-10)" "pK_(b1)=-log2.5xx10^(-12)`
`pK_(a1)=9.79" "pK_(b1)=11.6`
`pK_(a1)+pK_(b1)=14`
`pK_(a2)+11.6=14`
`pK_(a2)=2.3979`


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