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Grignard addition to carbonyl compounds is specific case of nucleophillic addition reaction which leads to formation of all type of alcohols (1^(@),2^(@) & 3^(@)) .In this addition the strongly nucleophlic Grignard reagent uses its electron pair to form a bond with theC - atom ofgtC=O group, where one e^(-) pair of group ,shifts out towards oxygen . It results in the formation of an intermediate species in which alkoxide ion associated withMg^(2+) and . Now addition of an intermediate of this species to give alcohol.Here P andQare respectively : |
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Answer»
![]() DIOL PROTECTS aldehyde since it is more REACTIVE. Grignard reagent reacts with keto carbon carbon since it does not REACT with (only oneequalent is given) |
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