Haemophilia is a sex linked recessive disorder of humans. The pedigree

1.	Haemophilia is a sex linked recessive disorder of humans. The pedigree chart given below shows the inheritance of haemophilia in one family. Study the pattern of inheritance and answer the questions given.(a) Give all the possible genotypes of the members 4, 5 and 6 in the pedigree chart. (b) A blood test shows that the individual 14 is a carrier of haemophilia. The member numbered 15 has recently married the member numbered 14. What is the probability that their first child will be a haemophilic male?
Answer» (a) Genotypes of member 4 – XX or XX^h Genotypes of member 5 – X^hY Genotypes of member 6 – XY (b) The probability of first child to be a haemophilic male is 25%.

Haemophilia is a sex linked recessive disorder of humans. The pedigree chart given below shows the inheritance of haemophilia in one family. Study the pattern of inheritance and answer the questions given.(a) Give all the possible genotypes of the members 4, 5 and 6 in the pedigree chart. (b) A blood test shows that the individual 14 is a carrier of haemophilia. The member numbered 15 has recently married the member numbered 14. What is the probability that their first child will be a haemophilic male?

Answer»

(a) Genotypes of member 4 – XX or XX^h

Genotypes of member 5 – X^hY

Genotypes of member 6 – XY

(b) The probability of first child to be a haemophilic male is 25%.

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