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Haemophilia is more commonly seen in human males than in human females becauseA. this disease is due to an X-linked dominant mutationB. a greater proportion of girls die in infancyC. this disease is due to an X-linked recessive mutationD. this disease is due to a Y-linked recessive mutation

Answer» Correct Answer - C
Haemophilia, hereditary (recessive X-linked) disease is caused due to fault in genes controlling the factor VIII and IX, located on X-chromosome. The male carries only one X-chromosome, other sex chromosome carries no genes for blood clotting, so the condition is usually seen only in males where only one faulty chromosome is needed.
While a female with one faulty X-chromosome will be carrier. So, in females two faulty X-chromosomes are needed to cause the disease.


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