How is the translation of mRNA terminated? Explain.

1.	How is the translation of mRNA terminated? Explain.
Answer» Termination of polypeptide ▪ When the A-site of ribosome reaches a termination codon which does not code for any amino acid, no charged tRNA binds to the A-site. ▪ Dissociation of polypeptide from ribosome takes place, which is catalysed by a ‘release factor’. ▪ There are three termination codons namely UGA, UAG and UAA.

Answer»

Termination of polypeptide

▪ When the A-site of ribosome reaches a termination codon which does not code for any amino acid, no charged tRNA binds to the A-site.

▪ Dissociation of polypeptide from ribosome takes place, which is catalysed by a ‘release factor’.

▪ There are three termination codons namely UGA, UAG and UAA.

Discussion