Ammonia is compatible with many, but not all materials suited to synthetic refrigerants. As an example, it is only compatible with some commonly used refrigeration system lubricants, excluding POLYOL ester (POE) and poly vinyl ether (PVE) lubricants, and it has only limited APPLICATIONS with poly alkylene glycol (PAG) lubricants.

To accommodate for the safety requirements in an R717 system, some modifications to an existing system design might be NEEDED to integrate safety features and ensure compatibility. Ammonia is not compatible with most types of electrical wiring insulation. Metals of construction inside ammonia systems normally are limited to carbon and stainless steel, but good compatibility of ammonia with copper and copper alloys in systems with careful moisture control have been reported, provided that there is no presence of water leading to copper corrosion. Aluminium is compatible with ammonia, but it is SENSITIVE to corrosion in water CIRCUITS due to the presence of chlorides.

Ammonia is compatible with many, but not all materials suited to synthetic refrigerants. As an example, it is only compatible with some commonly used refrigeration system lubricants, excluding polyol ester (POE) and poly vinyl ether (PVE) lubricants, and it has only limited applications with poly alkylene glycol (PAG) lubricants.

To accommodate for the safety requirements in an R717 system, some modifications to an existing system design might be needed to integrate safety features and ensure compatibility. Ammonia is not compatible with most types of electrical wiring insulation. Metals of construction inside ammonia systems normally are limited to carbon and stainless steel, but good compatibility of ammonia with copper and copper alloys in systems with careful moisture control have been reported, provided that there is no presence of water leading to copper corrosion. Aluminium is compatible with ammonia, but it is sensitive to corrosion in water circuits due to the presence of chlorides.