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InterviewSolution
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Name the kind of diseases/disorders and any two symptoms that are likely to occur in humans if: (a) Mutation in the gene that codes for an enzyme phenylalanine hydroxylase occurs. (b) The karyotype is XXY. |
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Answer» (a) Phenylalanine hydroxylase converts amino acid phenylalanine into another amino acid, tyrosine. It due to mutation, phenylalanine hydroxylase (PAH) does not form, Phenylalanine `overset("PAH")rarr` Tyrosine It leads to buildup of phenylalanine to toxic levels, a condition called phenylketonuria. The disease leads to mental disorders, seizures and intellectual disability. (b) The karyotype XXY is present in a syndrome called Klinefelter syndrome. It results from two or more X-chromosome in males. Symptoms include weaker muscles, greater height,less body hair, breast growth poor coordination and infertility. |
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