One of the following ring systems can be used as the bioisosteric repl

1.	One of the following ring systems can be used as the bioisosteric replacement benzene ring in drug design
Answer» Answer: The REPLACEMENT of para-substituted benzenes with saturated BI- and polycyclic bioisosteres – bicyclo[1.1. 1]pentane, bicyclo[2.2. 2]OCTANE and cubane, – often increases the potency, selectivity and metabolic stability of BIOACTIVE compounds.

One of the following ring systems can be used as the bioisosteric replacement benzene ring in drug design

Answer»

Answer:

The REPLACEMENT of para-substituted benzenes with saturated BI- and polycyclic bioisosteres – bicyclo[1.1. 1]pentane, bicyclo[2.2. 2]OCTANE and cubane, – often increases the potency, selectivity and metabolic stability of BIOACTIVE compounds.

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One of the following ring systems can be used as the bioisosteric replacement benzene ring in drug design

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