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Q.,Explain the following as used in medicinal chemistry (a) Lead compounds(b) Target molecules or drug targets. |
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Answer» In medicine, a chemical compound that shows promise as a treatment for a disease and may lead to the development of a new drug. THOUSANDS of compounds are tested in the laboratory to find a lead (“leading”) compound that may act on specific genes or proteins involved in a disease In medicinal CHEMISTRY, target MOLECULES or drug targets refer to the key molecules (such as carbohydrates, proteins, and nucleic acids) that are involved in certain metabolic pathways leading to certain DISEASES. These target molecules are INHIBITED when the drug molecules bind to the active sites. |
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