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Q3. You are chewing mint and drink a sip of waterand no matter how warm it is, the water feels icycold. Why does this happen?Q4. Write any three functions of saliva.​

Answer»

Answer:

Mint gum or CANDY might make EVERYTHING in your mouth feel sub-zero, but like the hot water that sometimes feels cold I wrote about in 2008, the feeling is just a thermal illusion that happens when our sensory receptors get fooled by stimuli.

At the heart of the minty matter is a PROTEIN called the transient RECEPTOR potential cation channel subfamily M member 8 (TRPM8), which is expressed in sensory neurons. TRPM8 is an ion channel, a type of protein that REGULATES the movement of ions across the membranes of cells. Just like only certain keys can open a lock on a door, only certain stimulants can open the ion channel and access the cell. TRPM8 opens in the presence of cold temperatures and allows Na+ and Ca2+ ions to enter the cell. This changes the electrical charge within the neuron and the information being sent from the neuron to the central nervous system, eventually leading to the perception of cold.



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