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Question : A woman with cystic fibrosis ,an autosomal recessive condition marries her first cosin.What is the risk that their first childwill have cystic fibrosis ?

Answer»

`1//4`
`1//2`
`3//4`
`1//8`

Solution :The gentoype of affected woman is cc. Her parents are obligate carries (Cc) and ONE of her grand parents must also be a carrier. Her FIRST cousin then has a 1/4 CHANCE being a carrier.He has 1/2 chance of transnmitting his c allete if it is present.So the chance of CHILD being a PATIENT of cystic fibrosis is `1//4xx1//2=1//8`


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