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Question : Briefly explain the structure of human insulin. What was the main challenge for production of insulin using rDNA technique?

Answer»

Solution :The HUMAN insulin is synthesized by the `beta` cells of ISLETS of Langerhans in the pancreas. It is formed of 51 aminoacids which are arranged in two polypeptide chains, A and B. The polypeptide CHAIN A has 21 amino acids while the polypeptide chain B has 30 amino acids. Both A and B chains are attached together by DISULPHIDE bonds.


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