Question : Calcium ion concentrationin blood affects muscle contraction .Does it lead to tetany in certain cases ? How will you correlate fluctuationin blood calcium with tetany ?

Question : Calcium ion concentrationin blood affects muscle contractio

1.	Question : Calcium ion concentrationin blood affects muscle contraction .Does it lead to tetany in certain cases ? How will you correlate fluctuationin blood calcium with tetany ?
Answer» Solution :For MUSCLE contraction opening of joining site of THIN filament is essential when `ca^(2+)` ions joins along with other regulatory protein troponim form troponincomplex . It REGULATES position of tropomyosin on thin filament union of `Ca^(2a)` re-arrangestropomysin-troponin complex , opening myosin linkge site on thin filament when `Ca^(2+)` is in cytosole , thin and thick filament SLIDE over each other , result in muscle contraction . When `Ca^(2+)` level decreases linkage surface coveredcontraction completed . In tetany `Ca^(2+)`level decrease in body fluid - due to inactiveness of parathyroid gland . This gland secrete parathormonehormone which regulates ca level in BLOOD . ,br> In tetany muscles are contracted /spasm and giddiness.