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Question : Depolarization means reversal of polarity. Mention the ionic charge on both sides of axolemma.

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Solution :Depolarization - Reversal of polarity
When a nerve fibre is stimulated, sodium voltage-gate opens and makes the axolemma permeable to `Na^(+)` ions, meanwhile the potassium voltage gate closes. As a result, the rate of LOW of `Na^(+)` ions into the AXOPLASM exceeds the rate of flow of `K^(+)` ions to the outside fluid [ECF]. Therefore, the axolemma BECOMES POSITIVELY charged inside and negatively charged outside. This reversal of ELECTRICAL charge is called Depolarization.


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