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Question : Describe the Frederick Griffith's experiment to show transformation in bacteria.

Answer»

Solution :In 1928 Frederich Griffith conducted some EXPERIMENTS to show that DNA is the molecule of inheritance `ul("Streptococcus") ul("pneumoniae")` has two strains virulent (or) smooth strain (S-TYPE) with gelatinous coat. The virulent is capable of producing the disease. The other strain is NON-virulent (or) rough type (R-type) without gelatinous coat, it is not capable of producing the disease.
1. When the virulent (S-type) pneumonia were injected into a mice, the mice died.
2. When the non virulent pneumonia were injected into a mice, the mice continued to live.
3. The virulent pneumonia was heated and killed and then it was injected into MOUSE,
4. The non virulent pneumonia and heat killed virulent pneumonia were together injected into the mouse, then the mouse died.
The heat killed virulent bacteria transferred the inheritance molecule into nonvirulent BACTERIAL, this process is called transferred, as a result mouse died of the disease.


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