Question : DNA is a polymer of nucleotides which are linked to each other by 3'-5' phosphodiester bond. To prevent polymerisation of nucleotides, which of the following modifications would you choose ?

Question : DNA is a polymer of nucleotides which are linked to each ot

1.	Question : DNA is a polymer of nucleotides which are linked to each other by 3'-5' phosphodiester bond. To prevent polymerisation of nucleotides, which of the following modifications would you choose ?
Answer» Replace purine with pyrimidines Remove/Replace 3' OH group in deoxy ribose Remove/Replace 2' OH group with some other group in deoxy ribose Both (B) and (C) Solution :Remove/Replace 3. OH group in deoxy ribose DNA is a polymer of NUCLEOTIDES which are LINKED to each other by 3.-5. phosphodiester bond. Remove/replace 3.OH group in deoxyribose, to PREVENT polymerisation of nucleotides.