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Question : Give explanation of synthesisof ATP in mitochondria.

Answer»

Solution :The energy RELEASED during the electron transport SYSTEM is utilised in synthesing ATPwith the help of ATP synthase (complex V).

This complex consists of two majorcomponents `F_(0) and F_(1)`.
The `F_(1) ` headpiece is a peripheral membrane protein complex and CONTAINS the site for synthesis of ATP from ADP and inorganic phosphate .`(ADP + Pi to ATP)`
`F_(0)` is an integral membrane protein complex thatforms the channel through whichprotons cross the inner membrane .
The passage of protons through and channel is COUPLED to the catalytic site of the `F_(1)` component for theproduction of ATP.
For each ATP produced `2H^(+)`passes through `F_(0)`fromthe intermembranespace to the matrix down the electrochemical protongradient.
THEREFORE ATP is synthesised.


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