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Question : Give information about Rh blood group. |
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Answer» Solution :This Antigen was actually found from the Rhesus monkeys. So it in named (RH - factor). Such Antigen is also observed on the surface of RBCs of humans. Such individuals are called RH positive. When this Antigen is absent in those are called Rh negative individuals. About 85% PEOPLE of human population are Rh positive and 15% people are Rh-nagative. An `Rh^(ve)` person if exposed to `Rh^(+ve)` blood, will FORM specific antibodies against the Rh antigens. Therefore the Rh group should also be matched before transfusion. A special case of Rh incompatibility has been observed betweed the `Rh^(-ve)` blood of the foetus. Rh antigents of the foetus do not get exposed to the `Rh^(-ve)` blood of the mother in the first pregnancy as the TWO bloods are well separated by placenta. in such cases, the mother starts preparing antibodies against in her blood. In cases of her subsequent pregnancies, the Rh antibodies from the mother, `RH^(+ve)` can leak into the blood of the foetus `RH^(+ve)` and destroy the foetal RBCs. This could be fatal to the foetus. This could case severe anaemia and jaundice to the baby. this coundition is called ERYTHROBLASTOSIS foetalis. This can be avoided by administering anti -RH antibodies to the mother immediately after the delivery of the first child. |
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