Question : How ADA deficiency cured by gene therapy? – InterviewSolution

InterviewSolution

1.	Question : How ADA deficiency cured by gene therapy?
Answer» Solution :Lymphocytes from the blood of the patient are grown in a culture OUTSIDE the BODY. A functional ADA C-DNA (using a retroviral vector) is then introduced into these lymphocytes which are subsequently returned to the patients. These CELLS are immortal, so the patient REQUIRES periodic infusions of genetically modified lymphocytes.

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