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Question : How did Eli Lilly synthesise the human insulin? Mention one difference between this insulin and the one produced by human pancreas. |
| Answer» Solution :ELI Lilly Company prepared two DNA sequences coding for chain A & B of human insulin and introduced il into the plasmids of E. coli, which was utilized to PRODUCE insulin. Insulin from an animal source caused allergy in some patients. In humans, insulin is SYNTHESISED as a prohormone which has one extra stretch called c-peptide. | |