InterviewSolution
Saved Bookmarks
| 1. |
Question : How is a polypeptide chain synthesis terminated during protein synthesis? |
| Answer» Solution :Synthesis of polypeptide chain terminates when a nonsense codon of mRNA reaches the A-site. There are three nonsense codon UAA, UAG and UGA, which are not recognized by any of the tRNAs. Therefore no more amino-acyl TRNA reaches the A site. The P site t-RNAs is hydrolysed and the completed polypeptide is RELEASED in the presence of GTP DEPENDENT release factor. | |